Physical Education
Hossein TaheriChadorneshin; Mohammad Esmaiel Afzalpour; Ehsan Afroozi-Gerow; Seyed Hosein Abtahi-Eivary; Meysam Alipour-Raz
Volume 26, Issue 1 , March and April 2019, , Pages 99-107
Abstract
Reactive oxygen species (ROS) result in serious damage oxidation of proteins, lipids and genomic structures. Studies have shown that production of ROS increases during intensive exercise training. The aim of present study was to investigate the effect of two type sprint and endurance exercise trainings ...
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Reactive oxygen species (ROS) result in serious damage oxidation of proteins, lipids and genomic structures. Studies have shown that production of ROS increases during intensive exercise training. The aim of present study was to investigate the effect of two type sprint and endurance exercise trainings on 8-oxoguanine DNA glycosylase (OGG1) and hydroxy-2'-deoxyguanosine (8-OHdG) levels in the brain and liver of Wistar rats. 24 adult Albino Wistar rats were randomly divided into sedentary control, sprint exercise training, and endurance exercise training groups. Rats in sprint and endurance exercise training groups ran on treadmill for 6 weeks, 6 days per week, at 80 to 100 percent of maximal oxygen consumption. OGG1 and 8-OHdG levels were measured using sandwich ELISA assay. Data analyzed using one way ANOVA at P≤0.05 level. Results showed that both of sprint and endurance exercise trainings result in significant increase in OGG1 levels in brain and liver. Sprint exercise training resulted in greater increase in brain OGG1 than endurance exercise training. However, sprint and endurance exercise training had no significant effect on 8-OHdG levels in brain and liver tissues. OGG1 content correlated negatively with 8-OHdG levels. Collectively, sprint and endurance exercise trainings prevents from genomic structure through an increase in OGG1 contents.
Physical Education
Hossein TaheriChadorneshin; mysam alipour raz; Mohammad Reza Yousefi; Sakineh Mokhtari-Motameni-Shivan
Volume 25, Issue 3 , July and August 2018, , Pages 441-450
Abstract
Background: Bruce and Cooper tests are used to determine the maximum oxygen consumption. However, the response of the indicators of muscle cell damage (Lactate dehydrogenase, Creatine kinase), cardiac (Creatine kinase-MB), and liver (Aspartate aminotransferase, Alanine aminotransferase and Alkaline phosphatase) ...
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Background: Bruce and Cooper tests are used to determine the maximum oxygen consumption. However, the response of the indicators of muscle cell damage (Lactate dehydrogenase, Creatine kinase), cardiac (Creatine kinase-MB), and liver (Aspartate aminotransferase, Alanine aminotransferase and Alkaline phosphatase) have not been compared following Bruce and Cooper tests.Materials and Methods: For this purpose, 18 sedentary male students (age: 20.88 ± 2.27 years, body mass index 22.67 ± 1.36 kg/m2), performed Bruce and Cooper protocols in two separate periods (one month interval). Blood sampling was taken before, immediately, 24 and 48 hours after each test. Serum concentrations of dependent variables were determined by commercial kits. Repeated measure and covariance analysis has been used to evaluated statistical difference in inter and intra group at P
Hossein Taheri Chadorneshin; Mohammad Esmaeel Afzalpour; Mohsen Foadodini; Hossein Abtahi
Volume 22, Issue 1 , March and April 2015, , Pages 180-188
Abstract
Background: Researches have showed that exercise trainings increase the brain-derived neurotrophic (BDNF) and glial cell-derived neurotrophic factor (GDNF) in the brain. In addition, hydrogen peroxide (H2O2) and tumor necrosis factor alpha (TNFα) increase protein content of BDNF and GDNF in vitro. However, ...
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Background: Researches have showed that exercise trainings increase the brain-derived neurotrophic (BDNF) and glial cell-derived neurotrophic factor (GDNF) in the brain. In addition, hydrogen peroxide (H2O2) and tumor necrosis factor alpha (TNFα) increase protein content of BDNF and GDNF in vitro. However, there is insufficient information about the interactive effects of high intensity exercise training, H2O2, and TNFα on neurotrophins. Hence, in the present study, we investigated the effect of high intensity intermittent training on the content of BDNF, GDNF, H2O2 and TNFα in the brain of albino wistar rats.
Materials and methods: Sixteen albino wistar rats divided into control and high intensity intermittent training groups. High intensity intermittent training has carried out for 6 weeks with 95 to 100% of maximum oxygen consumption on treadmill. BDNF, GDNF and TNFα contents have measured by sandwich ELISA method and H2O2 concentration by colorimetric method by commercial kits. Data analyzed using Student’s t-test, and p≤0.05 considered as statistically significant.
Results: High intensity intermittent training resulted in 75 and 143 percent increased in H2O2 (p